Living With Myeloma Or Kahler's Disease
Multiple Myeloma, also known as Kahler's disease is a malignant disorder. This disease affects the plasma blood cells and manifests commonly in people in the age bracket of 60-70 years. Multiple Myeloma is becoming common in instance around the world. The cancer slowly progresses from the bone marrow and makes it way to other parts of the body. The main reason behind the use of the term ‘multiple' in the name given to the cancer comes from the fact that it affects more than one bone at a time.
Today, around the world, there are a number of treatment options being experimented with to correct the condition in the early stages or contain the associated pain and deterioration of health in the alter stages. However, it is important to first understand the condition and research upon it to take a well informed decision. Although the incidence is rather rare under the age of 30, it is not impossible. Statistics on Multiple Myeloma reveal that the onslaught affects more males are affected than females.
The disease manifests ad the plasma blood tissues are infiltrated. The malignant cells that create the proliferation create abnormal immunoglobulins or paraproteins that in turn manifest internally in the form of IgG or IgA. The paraprotein thus created generates a series of auto-immune ailments. Also leading to platelet coating and related coagulation factors, Multiple Myeloma increases the instance of contracted infections. The disease is rated among the top life threatening diseases the world over.
Bringing on bone aches and plasma cell related pathological fractures; there are cases where the multiple osteolytic skull lesions have resulted in osteoclast stimulation. On the neurological front, the condition creates a compression of the spinal cord> this is triggered by vertebral lesion as there is infiltration of nerves by the infected plasma cells. Multiple Myeloma also triggers the onset of renal failure that mainly sets in due to the occurrence of hypercalcaemia, amyloidosis of kidneys and the development of a condition called pyelonephritis. This condition triggers susceptibility to infections and anemia.
Infection of the plasma cells can only be contained or treated through a dedicated bone marrow replacement and inhibition via radiotherapy and chemotherapy. The person shows a bleeding tendency that is mainly the result of coagulation factors brought on by paraproteins. On the serious cardio-vascular front it is not uncommon to see patients with Multiple Myeloma display signs and symptoms of Raynoud's phenomenon and the Hyperviscosity syndrome. In order to identify the ailment, it is essential to investigate the counts of increased ESR, calcium and uric acid in blood and alkaline phosphatase.
The patient also shows signs of multiple osteolytic lesions and these are best identified via x-rays. The effect of Multiple Myeloma on the bones of the vertebrae, pelvis and skull can be overwhelming if the disease is not detected in time. The various treatment options for the condition include chemo and radio therapies and drugs specially manufactured to contain the pain factor involved and improve the general health condition of the patient.